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Anxiety and Depression Affect 


 According to a recent study, over 50% of patients with autoimmune diseases also experience anxiety and depression, but the majority of them are never questioned about their mental health.


British researchers who polled over 1,800 patients discovered that over half of them seldom or never told their doctor about their mental health issues. This may indicate that a far greater range of neurological and mental health symptoms exist than has been previously documented.

According to a Cambridge news release, study co-author Dr. Melanie Sloan stated, "The low level of reporting we identified is a major concern as problems with mental health, fatigue, and cognition can be life-changing and sometimes life-threatening." She works in the public health and primary care department of the university.

Dr. Tom Pollak, another author, described the figures as "startling."

Pollak, who works at King's College London's Institute of Psychiatry, Psychology, & Neuroscience, said, "We have known for some time that having a systemic autoimmune disease can negatively affect one's mental health, but this study paints a startling picture of the breadth and impact of these symptoms."

"Everyone who provides care for these patients should regularly inquire about their mental health, and patients should be encouraged to express any concerns they may have without worrying about being judged. "No patient should endure suffering in silence," said Pollak.

1,853 patients with autoimmune rheumatic diseases, including lupus and rheumatoid arthritis, were surveyed for the study.

Questions about neurological and psychiatric symptoms were posed to them. A survey of almost 300 medical professionals, primarily neurologists, psychiatrists, and rheumatologists, was also conducted by the researchers, who also spoke with 113 medical professionals and patients.

The researchers inquired about depression, anxiety, hallucinations, and weariness.

It was discovered that 55% of the patients had depression, 57% had anxiety, 89% had extreme exhaustion, and 70% had cognitive dysfunction, or issues related to thinking and memory.

The rates exceeded the doctors' estimates by a significant margin. For instance, compared to the doctors' estimate of 15%, three times as many lupus patients reported having suicidal thoughts (47% versus 15%). The frequency and variety of symptoms patients reported to the researchers frequently took doctors by surprise and caused them concern.

The study's findings revealed that patients frequently hesitated to disclose mental health issues out of concern that they would be stigmatized. Even when patients did disclose their mental health symptoms, they frequently did not receive appropriate feedback or documentation, according to the patients.

"Feel guilty and useless, as well as depressed and very ill," one patient stated. I don't feel hopeful, understood, supported, or even heard at all. This is an awful way to live. Everything seems so hopeless."

According to Sloan, it's critical to recognize these unsaid issues.


We won't be able to assess the severity of these frequently undetected symptoms and assist patients in receiving the knowledge, support, and treatment they require unless we fully involve patients in their healthcare and solicit their opinions, according to Sloan.


The study was released in the journal Rheumatology on July 26.


What Proportion of Individuals Suffer from Autoimmune Diseases?


What proportion of individuals suffer from autoimmune diseases? An autoimmune disease affects about 8% of the population in the United States, and nearly 80% of those affected are women. Depending on the source, the list of autoimmune diseases can contain between 80 and 150 chronic, often crippling conditions that have no known cure.


 Which Autoimmune Disease Is the Most Prevalent?

Although there are more than a hundred varieties of autoimmune diseases, the following are the most prevalent ones:
Colitis and Crohn's disease are examples of inflammatory bowel diseases.
arthritis rheumatoid (RA)
Lupin disease.
diabetes type 1.
MS, or multiple sclerosis
Scleroderma.
psoriasis.
arthritis psoriatic.

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Who Is a Victim of an Autoimmune Illness?

The Association Between Women and Autoimmune Disease

Physicians are unsure of the underlying causes of autoimmune diseases, including why women are more likely than men to develop them. One theory suggests that women may be more prone to autoimmune diseases due to higher hormone levels, particularly during the childbearing years.



Who Is More Susceptible to Autoimmune Disorders?

Who is more susceptible to autoimmune disorders? Women are more likely than men to suffer from many autoimmune diseases. Autoimmune diseases are prevalent in the United States, affecting 1 in 15 individuals. In the United States, 1.4 million people have ulcerative colitis or Crohn's disease, and one million have lupus.


More information


For more on mental health and autoimmune diseases, head to the Global Autoimmune Institute.

SOURCES: University of Cambridge, news release, July 26, 2023

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